About us
My moto: "Wisdom is not a product of schooling but on the lifelong attempt to acquire it"
Em. Prof. Marc Quirynen
Professor M. Quirynen graduated in 1980 as a dentist from the Catholic University of Leuven, where he also completed his training in Periodontology in 1984. In 1986, he earned his PhD with a dissertation titled “Anatomical and Inflammatory Factors Influencing Bacterial Plaque Growth and Retention in Humans.” He is currently part-time engaged in the post-graduate programme of Periodontology at the Catholic University of Leuven (Belgium), and visiting professor at Egas Moniz University of Lisbon (Portugal).
His key international lectures are: Etiology and Treatment of Oral Malodour, Multi-Causality of Peri-Implantitis (including iatrogenic factors and peri-apical peri-implantitis), A Peri-Implantitis Risk Assessment Tool, One-Stage, Full-Mouth Disinfection, Plaque Growth Modifiers, Limitations of GBR, Guided implant surgery, Overdentures, Second Class Therapy?.
He has published over 450 full papers in international peer-reviewed journals (H-index: Web of Science 85, Research gate: 116).
Currently, Professor Quirynen's research emphasizes the use of autologous platelet concentrates in periodontal surgery, including dental implants. He recently published a book titled “Leucocyte- and Platelet-Rich Fibrin (L-PRF) in Oral Regenerative Procedures” and is the editor of a special Perio 2000 issue on "Autologous Platelet Concentrates," which verifies the scientific evidence for their clinical use.
He regularly gives full-day courses on the use of L-PRF in dental surgery, highlighting the most optimal protocols for L-PRF preparation and step-by-step instructions for each oral application.
The Periodontology team of Leuven.
Prof. Ana Castro
Mrs. Christel Dekeyser
Prof. Andy Temmerman
Prof. Wim Teughels
The Periodontology Department of Leuven offers a three-year, full-time specialty training program accredited by the European Federation of Periodontology. The department is led by Prof. Wim Teughels, the current chairman. Prof. Ana Castro oversees the clinic, Prof. A. Temmerman supervises research activities, and Mrs. Christel Dekeyser serves as the full-time manager of the clinic.
Research on L-PRF has been primarily conducted by Catherine Andrade, Ana Castro, Simone Cortellini, Rutger D’Hondt, Manoetjer Siawasch, Andy Temmerman, Mihai Tarce, and Jize Yu. Special thanks to my friend Nelson Pinto for the early assistance and insightful discussions, which were instrumental in developing this website.
Research is a team approach involving the entire staff, with a significant contribution from everyone including lab technician, secretariat, postgraduate students in Periodontology, PhD students, statistician, .... However, a good live-work balance is mandatory.
My history with L-PRF
In 2012, I was introduced to L-PRF by Professor Nelson Pinto, marking the beginning of an extraordinary journey in my career. Despite mixed feedback from the scientific community, my department organized the first ENHD congress in 2016, followed by another successful meeting in 2018, to demonstrate L-PRF's potential. To further validate L-PRF, Nelson and I co-authored a comprehensive book in 2022, detailing its applications and benefits. In 2025, I edited a special issue of the Perio 2000 journal, providing in-depth scientific evidence supporting L-PRF.
To disseminate this knowledge, I created this open-access website featuring detailed clinical recommendations, supported by evidence-based research and illustrated with cases and videos. This platform aims to guide healthcare providers across various disciplines in effectively utilizing L-PRF.
Online ISSN: 1600-0757,
Print ISSN: 0906-6713.
ISBN: 978-1-78698-105-9
My mission & intention
My mission is to convince clinicians to integrate L-PRF into their practice. By conducting research with minimal financial support and maximum scientific freedom, I aim to expand the scientific evidence for this innovative concept, highlighting its significant benefits for patients.
Additionally, I seek to demonstrate L-PRF's advantages in wound healing to colleagues in other medical fields, hoping to alleviate and shorten patient suffering. Current observations on L-PRF's impact on treating non-responding chronic wounds and burns, indeed, underscore its potential. This, in my view, is the ultimate goal of an academician.
My intention with developing this website, similar to my book, without industry interference and solely guided by evidence-based data, was to reach more clinicians and patients. I hope that after exploring the website, clinicians will feel more confident using L-PRF, as it simplifies their work, making surgery less technique-dependent, more forgiving of mistakes, and less stressful.
More importantly, it will better serve patients with fewer complications, lower morbidity, less pain, faster healing, and potentially lower treatment costs. The small patient section of the website is designed only to inform them about this novel technique and provide some useful information for discussions with their healthcare providers.
Over the past decade, numerous modifications of the original L-PRF preparation protocol have emerged from various companies. However, as there is currently no scientific evidence of a different impact on clinical outcomes, and given that they all contain leukocytes and platelets, I consider them equal members of the L-PRF family and treat them as such.
Acknowledgement:
This website was set-up by Jeroen Van der Putten, IT specialist.
Technical web support by Kris Cabus.
Bianca Thys is responsible for the corrections and "look and feel" of the website.